Associate Scientist, Translational Sciences- Immunology

Company: Disability Solutions
Location: San Diego
Posted on: May 18, 2024

Job Description:

Johnson & Johnson is currently seeking an Associate Scientist to join our Translational Sciences (TS), Immunology Translational Sciences and Medicine (TSM) team located in San Diego, CA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at Immunology has a history of bringing life-changing therapies to patients with immune-mediated diseases. Translational Sciences and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end-to-end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies for these patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. It has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development. This position will reside within the GI group in Immunology Translational Sciences department and requires a highly motivated and detail-orientated candidate to for the clinical progression of innovative therapies across immunologic diseases. The successful candidate will be expected to contribute to the execution of biomarker plans and bring an enthusiastic mindset to the team. The successful candidate will be effective in the execution and troubleshooting of lab experiments for human-based in vitro/ex vivo stimulation models and perform ELISA-based assays and proteomics/transcriptomics experiments, including Olink and RNAseq. Further, the candidate will operate in a highly collaborative environment with members of TS and the Discovery organization and will follow best practices for Data Integrity complying with organization and company standard operating procedures in a timely fashion, such as training and project time accounting. Responsibilities are as follows:

• Support implantation of Olink platform (target and explore) at La Jolla for serum proteomics analysis and internalizing ELISA-based clinical assays at La Jolla site
• Perform experiments to support biomarker programs across various stages of clinical trials and provide biomarker data packages in timely manner with high quality
• Execute, and troubleshoot molecular and/or cellular assays for patient stratification in clinical trials for the Immunology Therapeutic Area
• Work closely with other lab-based personnel within Biomarkers to ensure optimal laboratory environment (collaboration, culture, safety, etc.)

Keywords: Disability Solutions, Calexico , Associate Scientist, Translational Sciences- Immunology, Healthcare , San Diego, California